First topical preventive therapy for menstrual migraine
- Two-thirds of premenopausal female migraine sufferers self-report that migraine attacks consistently occur during around menses.
- These headaches have been referred to as “menstrual migraine.”
- Menstrual migraine attacks are more severe, disabling, and refractory to abortive medications than those that are non-menses related.
-
33%
Suffer Episodic Migraines
- Approximately 33 Million Patients
- 4 -14 Migraines / Month
- >80% treated with RX Therapies
- 50% (7.8 mil) = Menstrual Migraine
-
60%
Suffer Acute Migraines
- Approximately 23 Million Patients
- Less than 4 Migraines / Month
- 50% treated with OTC medication
-
8%
Suffer Chronic Migraines
- Approximately 3 Million Patients
- More than 15 Migraines / Month
- 100% treated with RX Therapy
Strategies for Migraine Treatment
- NSAIDs have been shown to provide efficacy in menstrual migraine but limited by systemic toxicity.
- Non-systemic topically applied therapies are ideal for chronic use.
Topofen™ has shown efficacy in the treatment
and prophylaxis of migraine
Achelios Therapeutics aims to overcome this and other pain-related conditions.