It is estimated that about one in five or about 1.5 billion people, globally, suffer from chronic pain (CP).
Chronic pain affects approximately 100 million Americans at one time or another. One in four people face pain on a daily basis. Of this, 33% is due to back pain, 30% to joint arthritis, and the rest to other conditions such as accidents, spine, neurological, and neuropathic pain.
In the US, the primary analgesics employed for treating chronic pain are opiates and oral nonsteroidal anti-inflammatory drugs (NSAIDS).
Both classes of drugs can produce severe side effects. NSAIDS can cause gastric ulceration and renal damage; opioids can cause nausea, constipation, confusion, and dependency problems.
100 Million Adults Suffer from Chronic Pain in the United States